Robertson, Avril A B: search on Z-Library

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1

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

Coll, Rebecca C, Robertson, Avril A B, Chae, Jae Jin, Higgins, Sarah C, Muñoz-Planillo, Raúl, Inserra, Marco C, Vetter, Irina, Dungan, Lara S, Monks, Brian G, Stutz, Andrea, Croker, Daniel E, Butler,

Journal:

Nature Medicine

Year:

2015

Language:

english

File:

PDF, 1.80 MB

english, 2015

2

GMP Synthase Is Required for Virulence Factor Production and Infection by Cryptococcus neoformans

Chitty, Jessica L., Tatzenko, Tayla L., Williams, Simon J., Koh, Y. Q. Andre E., Corfield, Elizabeth C., Butler, Mark S., Robertson, Avril A. B., Cooper, Matthew A., Kappler, Ulrike, Kobe, Bostjan, Fr

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 4.43 MB

english, 2017

3

From evidence to policy: The Scottish national naloxone programme

McAuley, Andrew, Best, David, Taylor, Avril, Hunter, Carole, Robertson, Roy

Journal:

Drugs Education Prevention and Policy

Year:

2012

Language:

english

File:

PDF, 497 KB

english, 2012

4

Characterisation of small molecule ligands 4CMTB and 2CTAP as modulators of human FFA2 receptor signalling

Schofield, Zoe V., Croker, Daniel, Robertson, Avril A. B., Massey, Nicholas L., Donovan, Chantal, Tee, Ernest, Edwards, David, Woodruff, Trent M., Halai, Reena, Hansbro, Philip M., Cooper, Matthew A.

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 1.86 MB

english, 2018

5

MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition

Coll, Rebecca C., Hill, James R., Day, Christopher J., Zamoshnikova, Alina, Boucher, Dave, Massey, Nicholas L., Chitty, Jessica L., Fraser, James A., Jennings, Michael P., Robertson, Avril A. B., Schr

Journal:

Nature Chemical Biology

Year:

2019

Language:

english

File:

PDF, 2.37 MB

english, 2019

6

Natural product and natural product derived drugs in clinical trials

Butler, Mark S., Robertson, Avril A. B., Cooper, Matthew A.

Journal:

Natural Product Reports

Year:

2014

Language:

english

File:

PDF, 4.67 MB

english, 2014

7

Inflammasomes in the lung

Pinkerton, James W., Kim, Richard Y., Robertson, Avril A.B., Hirota, Jeremy A., Wood, Lisa G., Knight, Darryl A., Cooper, Matthew A., O’Neill, Luke A.J., Horvat, Jay C., Hansbro, Philip M.

Journal:

Molecular Immunology

Year:

2017

Language:

english

File:

PDF, 1.51 MB

english, 2017

8

A multicomponent toxin from Bacillus cereus incites inflammation and shapes host outcome via the NLRP3 inflammasome

Mathur, Anukriti, Feng, Shouya, Hayward, Jenni A., Ngo, Chinh, Fox, Daniel, Atmosukarto, Ines I., Price, Jason D., Schauer, Kristina, Märtlbauer, Erwin, Robertson, Avril A. B., Burgio, Gaetan, Fox, Ed

Journal:

Nature Microbiology

Year:

2018

Language:

english

File:

PDF, 3.92 MB

english, 2018

9

Non-canonical Caspase-1 Signaling Drives RIP2-Dependent and TNF-Î±-Mediated Inflammation InÂ Vivo

Reinke, SÃ¶ren, Linge, Mary, Diebner, Hans H., Luksch, Hella, Glage, Silke, Gocht, Anne, Robertson, Avril A.B., Cooper, Matthew A., Hofmann, Sigrun R., Naumann, Ronald, Sarov, Mihail, Behrendt, Rayk,

Journal:

Year:

2020

Language:

english

File:

PDF, 3.52 MB

english, 2020

10

Evaluation of liquid chromatography–atmospheric pressure chemical ionisation–mass spectrometry for the identification and quantification of desulphoglucosinolates

D. Wynne Griffiths, Henry Bain, Nigel Deighton, Nigel P. Botting, Avril A. B. Robertson

Journal:

Phytochemical Analysis

Year:

2000

Language:

english

File:

PDF, 109 KB

english, 2000

11

Cryptococcus neoformans ADS lyase in an enzyme essential for virulence whose crystal structure reveals features exploitable in antifungal drug design

Chitty, Jessica L, Blake, Kirsten L, Blundell, Ross D, Koh, Y.Q. Andre E, Thompson, Merinda, Robertson, Avril A.B, Butler, Mark S, Cooper, Matthew A, Kappler, Ulrike, Williams, Simon J, Kobe, Bostjan,

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 934 KB

english, 2017

12

Compromised NLRP3 and AIM2 inflammasome function in autoimmune NZB/W F1 mouse macrophages

Thygesen, Sara J., Takizawa, Karli E., Robertson, Avril A.B., Sester, David P., Stacey, Katryn J.

Journal:

Immunology & Cell Biology

Year:

2018

Language:

english

File:

PDF, 751 KB

english, 2018

13

NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice

Mridha, Auvro R., Wree, Alexander, Robertson, Avril A.B., Yeh, Matthew M., Johnson, Casey D., Van Rooyen, Derrick M., Haczeyni, Fahrettin, Teoh, Narci C.-H., Savard, Christopher, Ioannou, George N., M

Journal:

Journal of Hepatology

Year:

2017

Language:

english

File:

PDF, 2.22 MB

english, 2017

14

The synthesis of isotopically labelled glucosinolates for analysis and metabolic studies

Nigel P. Botting, Avril A. B. Robertson, John J. Morrison

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2007

Language:

english

File:

PDF, 99 KB

english, 2007

15

Chick Embryo: A Preclinical Model for Understanding Ischemia-Reperfusion Mechanism

Fauzia, Eram, Barbhuyan, Tarun Kumar, Shrivastava, Amit Kumar, Kumar, Manish, Garg, Paarth, Khan, Mohsin Ali, Robertson, Avril A. B., Raza, Syed Shadab

Journal:

Frontiers in Pharmacology

Year:

2018

Language:

english

File:

PDF, 4.56 MB

english, 2018

16

NLRP3 inflammasome inhibition with MCC950 improves insulin sensitivity and inflammation in a mouse model of frontotemporal dementia

Hull, Claire, Dekeryte, Ruta, Buchanan, Heather, Kamli-Salino, Sarah, Robertson, Avril, Delibegovic, Mirela, Platt, Bettina

Journal:

Neuropharmacology

Year:

2020

File:

PDF, 6.76 MB

2020

17

Between breed genetic variation for welfare-related behavioural traits in domestic fowl

Paul M. Hocking, Caroline E. Channing, Graeme W. Robertson, Avril Edmond, R.Bryan Jones

Journal:

Applied Animal Behaviour Science

Year:

2004

Language:

english

File:

PDF, 158 KB

english, 2004

18

Targeting the NLRP3 Inflammasome With Inhibitor MCC950 Prevents Aortic Aneurysms and Dissections in Mice

Ren, Pingping, Wu, Darrell, Appel, Richard, Zhang, Lin, Zhang, Chen, Luo, Wei, Robertson, Avril A. B., Cooper, Matthew A., Coselli, Joseph S., Milewicz, Dianna M., Shen, Ying H., LeMaire, Scott A.

Journal:

Journal of the American Heart Association

Year:

2020

File:

PDF, 5.68 MB

2020

19

An unusual cause of anaesthetic death in a horse

SHEILAH A. ROBERTSON, AVRIL E. WATERMAN, J. G. LANE, P. J. BROWN

Journal:

Equine Veterinary Journal

Year:

1985

Language:

english

File:

PDF, 328 KB

english, 1985

20

Cytokine release inhibitor drug, CRID3, inhibits the NLRP3 inflammasome in glia

Dempsey, Colin, Coll, Rebecca, Robertson, Avril, Cooper, Matthew, O'Neill, Luke, Lynch, Marina

Journal:

Journal of Neuroimmunology

Year:

2014

Language:

english

File:

PDF, 48 KB

english, 2014

21

Human Monocytes Engage an Alternative Inflammasome Pathway

Gaidt, Moritz M., Ebert, Thomas S., Chauhan, Dhruv, Schmidt, Tobias, Schmid-Burgk, Jonathan L., Rapino, Francesca, Robertson, Avril A.B., Cooper, Matthew A., Graf, Thomas, Hornung, Veit

Journal:

Year:

2016

Language:

english

File:

PDF, 3.95 MB

english, 2016

22

Inflammasome-Independent Role for NLRP3 in Controlling Innate Antihelminth Immunity and Tissue Repair in the Lung

Chenery, Alistair L., Alhallaf, Rafid, Agha, Zainab, Ajendra, Jesuthas, Parkinson, James E., Cooper, Martha M., Chan, Brian H. K., Eichenberger, Ramon M., Dent, Lindsay A., Robertson, Avril A. B., Kup

Journal:

The Journal of Immunology

Year:

2019

Language:

english

File:

PDF, 2.31 MB

english, 2019

23

The Endoplasmic Reticulum-Mitochondrion Tether ERMES Orchestrates Fungal Immune Evasion, Illuminating Inflammasome Responses to Hyphal Signals

Tucey, Timothy M., Verma-Gaur, Jiyoti, Nguyen, Julie, Hewitt, Victoria L., Lo, Tricia L., Shingu-Vazquez, Miguel, Robertson, Avril A. B., Hill, James R., Pettolino, Filomena A., Beddoe, Travis, Cooper

Journal:

Year:

2016

Language:

english

File:

PDF, 3.95 MB

english, 2016

24

Synthesis and evaluation of NLRP3-inhibitory sulfonylurea [11C]MCC950 in healthy animals

Hill, James R., Shao, Xia, Massey, Nicholas L., Stauff, Jenelle, Sherman, Phillip S., Robertson, Avril A.B., Scott, Peter J.H.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2020

File:

PDF, 1.14 MB

2020

25

Synthesis of deuterium labelled desulfoglucosinolates as internal standards for LC-MS analysis

Avril A.B. Robertson, Nigel P. Botting

Journal:

Year:

1999

Language:

english

File:

PDF, 1.02 MB

english, 1999

26

The NLRP3 Inflammasome Suppresses Protective Immunity to Gastrointestinal Helminth Infection

Alhallaf, Rafid, Agha, Zainab, Miller, Catherine M., Robertson, Avril A.B., Sotillo, Javier, Croese, John, Cooper, Matthew A., Masters, Seth L., Kupz, Andreas, Smith, Nicholas C., Loukas, Alex, Giacom

Journal:

Year:

2018

Language:

english

File:

PDF, 4.35 MB

english, 2018

27

Antifungal Benzo[b]thiophene 1,1-dioxide IMPDH Inhibitors Exhibit Pan-Assay Interference (PAINS) Profiles

Kummari, Lalith K., Butler, Mark S., Furlong, Emily, Blundell, Ross, Nouwens, Amanda, Silva, Alberto B., Kappler, Ulrike, Fraser, James A., Kobe, Bostjan, Cooper, Matthew A., Robertson, Avril A.B.

Journal:

Bioorganic & Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.44 MB

english, 2018

28

Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice

Gordon, Richard, Albornoz, Eduardo A., Christie, Daniel C., Langley, Monica R., Kumar, Vinod, Mantovani, Susanna, Robertson, Avril A. B., Butler, Mark S., Rowe, Dominic B., O’Neill, Luke A., Kanthasam

Journal:

Science Translational Medicine

Year:

2018

Language:

english

File:

PDF, 1.67 MB

english, 2018

29

IL-1β is an innate immune sensor of microbial proteolysis

LaRock, Christopher N., Todd, Jordan, LaRock, Doris L., Olson, Joshua, O’Donoghue, Anthony J., Robertson, Avril A. B., Cooper, Matthew A., Hoffman, Hal M., Nizet, Victor

Journal:

Science Immunology

Year:

2016

Language:

english

File:

PDF, 1.02 MB

english, 2016

30

Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage and dysfunction in salt-sensitive hypertension

Krishnan, Shalini M, Ling, Yeong H, Huuskes, Brooke M, Ferens, Dorota, Saini, Narbada, Chan, Christopher T, Diep, Henry, Kett, Michelle M, Samuel, Chrishan S, Kemp-Harper, Barbara K, Robertson, Avril

Journal:

Cardiovascular Research

Year:

2018

Language:

english

File:

PDF, 15.21 MB

english, 2018

31

NLRP3-inflammasome inhibition prevents high fat and high sugar diets-induced heart damage through autophagy induction

Pavillard, Luís E., Cañadas-Lozano, Diego, Alcocer-Gómez, Elísabet, Marín-Aguilar, Fabiola, Pereira, Sheila, Robertson, Avril A.B., Muntané, Jordi, Ryffel, Bernhard, Cooper, Matthew A., Quiles, José L

Journal:

Year:

2017

Language:

english

File:

PDF, 5.30 MB

english, 2017

32

Tissueâresident macrophages actively suppress ILâ1beta release via a reactive prostanoid/ILâ10 pathway

Ipseiz, Natacha, Pickering, Robert J, Rosas, Marcela, Tyrrell, Victoria J, Davies, Luke C, Orr, Selinda J, Czubala, Magdalena A, Fathalla, Dina, Robertson, Avril AB, Bryant, Clare E, O'Donnell, Valeri

Journal:

The EMBO Journal

Year:

2020

File:

PDF, 1.19 MB

2020

33

Antimicrobial octapeptin C4 analogues active against Cryptococcus species

Chitty, Jessica L., Butler, Mark S., Suboh, Azzah, Edwards, David J., Cooper, Matthew A., Fraser, James A., Robertson, Avril A. B.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2017

Language:

english

File:

PDF, 1.16 MB

english, 2017

34

Synthesis of deuterium-labelled analogues of NLRP3 inflammasome inhibitor MCC950

Salla, Manohar, Butler, Mark S., Massey, Nicholas L., Reid, Janet C., Cooper, Matthew A., Robertson, Avril A.B.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2017

Language:

english

File:

PDF, 756 KB

english, 2017

35

30

Coll, Rebecca C., Robertson, Avril A.B., Chae, Jae Jin, Higgins, Sarah C., Dungan, Lara S., Muñoz-Planillo, Raul, Monks, Brian G., Croker, Daniel E., Sutton, Caroline E., Stutz, Andrea, Nunez, Gabriel

Journal:

Year:

2014

Language:

english

File:

PDF, 45 KB

english, 2014

36

NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase-4 and caspase-5

Baker, Paul J., Boucher, Dave, Bierschenk, Damien, Tebartz, Christina, Whitney, Paul G., D'Silva, Damian B., Tanzer, Maria C., Monteleone, Mercedes, Robertson, Avril A. B., Cooper, Matthew A., Alvarez

Journal:

European Journal of Immunology

Year:

2015

Language:

english

File:

PDF, 684 KB

english, 2015

37

An optimized whole blood assay measuring expression and activity of NLRP3, NLRC4 and AIM2 inflammasomes

Grinstein, Lev, Luksch, Hella, Schulze, Felix, Robertson, Avril A.B., Cooper, Matthew A., Rösen-Wolff, Angela, Winkler, Stefan

Journal:

Clinical Immunology

Year:

2017

Language:

english

File:

PDF, 970 KB

english, 2017

38

MCC950, a specific small molecule inhibitor of NLRP3 inflammasome attenuates colonic inflammation in spontaneous colitis mice

Perera, Agampodi Promoda, Fernando, Ruchira, Shinde, Tanvi, Gundamaraju, Rohit, Southam, Benjamin, Sohal, Sukhwinder Singh, Robertson, Avril A. B., Schroder, Kate, Kunde, Dale, Eri, Rajaraman

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 3.71 MB

english, 2018

39

Inflammasome-Independent Role for NLRP3 in Controlling Innate Antihelminth Immunity and Tissue Repair in the Lung

Chenery, Alistair L., Alhallaf, Rafid, Agha, Zainab, Ajendra, Jesuthas, Parkinson, James E., Cooper, Martha M., Chan, Brian H. K., Eichenberger, Ramon M., Dent, Lindsay A., Robertson, Avril A. B., Kup

Journal:

The Journal of Immunology

Year:

2019

File:

PDF, 2.31 MB

2019

40

Caspase-1-dependent inflammasomes mediate photoreceptor cell death in photo-oxidative damage-induced retinal degeneration

Wooff, Yvette, Fernando, Nilisha, Wong, Josephine H. C., Dietrich, Catherine, Aggio-Bruce, Riemke, Chu-Tan, Joshua A., Robertson, Avril A. B., Doyle, Sarah L., Man, Si Ming, Natoli, Riccardo

Journal:

Scientific Reports

Year:

2020

File:

PDF, 12.08 MB

2020

41

Efficient synthesis of anacardic acid analogues and their antibacterial activities

Mamidyala, Sreeman K., Ramu, Soumya, Huang, Johnny X., Robertson, Avril A.B., Cooper, Matthew A.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 703 KB

english, 2013

42

Multiple inflammasomes may regulate the interleukin-1-driven inflammation in protracted bacterial bronchitis

Chen, Alice C-H., Tran, Hai B., Xi, Yang, Yerkovich, Stephanie T., Baines, Katherine J., Pizzutto, Susan J., Carroll, Melanie, Robertson, Avril A.B., Cooper, Matthew A., Schroder, Kate, Simpson, Jodie

Journal:

ERJ Open Research

Year:

2018

Language:

english

File:

PDF, 808 KB

english, 2018

43

Metabolic competition between host and pathogen dictates inflammasome responses to fungal infection

Tucey, Timothy M., Verma, Jiyoti, Olivier, FranÃ§ios A. B., Lo, Tricia L., Robertson, Avril A. B., Naderer, Thomas, Traven, Ana, Hohl, Tobias M.

Journal:

Year:

2020

File:

PDF, 13.42 MB

2020

44

High-performance liquid chromatographic separation of natural and synthetic desulphoglucosinolates and their chemical validation by UV, NMR and chemical ionisation-MS methods

Guy Kiddle, Richard N. Bennett, Nigel P. Botting, Nicola E. Davidson, Avril A. B. Robertson, Roger M. Wallsgrove

Journal:

Phytochemical Analysis

Year:

2001

Language:

english

File:

PDF, 191 KB

english, 2001

45

Pharmacological characterisation of small molecule C5aR1 inhibitors in human cells reveals biased activities for signalling and function

Li, Xaria X., Lee, John D., Massey, Nicholas L., Guan, Carolyn, Robertson, Avril A.B., Clark, Richard J., Woodruff, Trent M.

Journal:

Biochemical Pharmacology

Year:

2020

File:

PDF, 1.59 MB

2020

46

Role for NLRP3 Inflammasome-mediated, IL-1β-dependent Responses in Severe, Steroid-resistant Asthma

Kim, Richard Y, Pinkerton, James W, Essilfie, Ama T, Robertson, Avril AB, Baines, Katherine J, Brown, Alexandra C, Mayall, Jemma R, Ali, Md. Khadem, Starkey, Malcolm R, Hansbro, Nicole G, Hirota, Jere

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2017

Language:

english

File:

PDF, 3.96 MB

english, 2017

47

The Bohlmann–Rahtz route to functionalised pyridine scaffolds and their use in library synthesis

Katherine E. Bashford, Matthew B. Burton, Stuart Cameron, Anthony L. Cooper, Rebecca D. Hogg, Peter D. Kane, David A. MacManus, Christopher A. Matrunola, Christopher J. Moody, Avril A.B. Robertson, Ma

Journal:

Tetrahedron Letters

Year:

2003

Language:

english

File:

PDF, 155 KB

english, 2003

48

Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition

Tate, Michelle D., Ong, James D. H., Dowling, Jennifer K., McAuley, Julie L., Robertson, Avril B., Latz, Eicke, Drummond, Grant R., Cooper, Matthew A., Hertzog, Paul J., Mansell, Ashley

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.02 MB

english, 2016

49

Design, Synthesis and Evaluation of an NLRP3 Inhibitor Diazirine Photoaffinity Probe

Hill, James R., Coll, Rebecca C., Schroder, Kate, Robertson, Avril A.B.

Journal:

Tetrahedron Letters

Year:

2020

Language:

english

File:

PDF, 539 KB

english, 2020

50

The synthesis of glucosinolates deuterium labelled in the glucose fragment

Avril A. B. Robertson, Nigel P. Botting

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2006

Language:

english

File:

PDF, 157 KB

english, 2006

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